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Is Rogaine causing the cancer?

Dear Dr. Roach: I’m a female who has used Rogaine for 24 years. For the past two, I have been using 5%, per my dermatologist. I have had three Mohs surgeries on my scalp in the past two years to remove basil cell carcinomas. I also use a semi-permanent color on my hair.

Could the Rogaine be causing the cancer? From what I can find out it doesn’t. — L.J.

Answer: Basal cell cancer is the most common skin cancer. The major risk factor is sunlight, and scalp cancers are usually due to sun exposure, especially in people with fair skin or hair or who have thinning hair. I could find no association with either minoxidil or hair dyes. Staying out of the sun or using head protection (a hat) will help reduce risk.

Dear Dr. Roach: My husband successfully completed 45 days of radiation for prostate cancer. His last PSA was non-detectable. He has to take medication for two years as part of the cure. However, it is causing him to have horrible hot flashes and night sweats. The usual over-the-counter solutions for women do not seem to be helping at all. Would you suggest something designed for a male? — P.B.

Answer: The first effective treatment for prostate cancer was depriving the cancer cells of androgens, which was initially done surgically, by removing the testes. It is done now with medications that act like gonadotropin-releasing hormone. Although these initially stimulate testosterone production, their continued use causes lower levels of testosterone, and within a month testosterone levels drop to the same levels as in men who have had surgery to remove their testes.

Hot flashes occur in 80% of men and can be very disruptive. Treatments that are effective for women are often not effective in men, as you observed. The best-studied and most effective treatments in men were medroxyprogesterone (a hormone that opposes some actions of estrogen) and cyproterone (an antiandrogen available in Canada, but not the U.S.). It reduced hot flashes by 84% to 95% in men. Venlafaxine, normally used as an antidepressant, reduced symptoms by 50%, and gabapentin, used for epilepsy or for nerve pain, reduced symptoms by about 45%.

It’s very important to treat the symptoms so he can continue this treatment, which is part of his best chance for long-term remission from prostate cancer.

Starting at $3.95/week.

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